• Hyphema (RBCs in anterior chamber): from trauma, inflammation, pathologic neovascularization

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  • Hypopyon (layered WBCs in anterior chamber): concerning for serious infection (infectious keratitis, bacterial endophthalmitis, etc), often post-op

  • Iritis (inflammation of anterior uveal tract): can be caused by trauma, infection, inflammation, infiltrative process. Usually no discharge. Cardinal sign is ciliary flush (injected ring around iris)

  • Acute angle-closure glaucoma (inadequate drainage of aqueous humor leads to rapid increase in intraocular pressure): often distressed w/ dull unilateral headache rather than eye pain. Pupil fixed in mid-dilation. Cornea will become “hazy” from edema. May also see ciliary flush.

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