You are discussing the risk of intracranial hemorrhage with tPA administration with a patient and her family:

79 y/o Asian female

NIH stroke scale of 7

Systolic BP of 140

Blood glucose < 100

What is her risk of symptomatic intracranial hemorrhage with tPA administration according to the NIH GRASPS method (one proposed tool for calculating risk)?  HINT: Use table 1 from the article (link below).  Scroll down for answer.

Article link:


Answer: 3%