Our Research

National, multicenter prospective cohort of ED patients with confirmed fentanyl analog exposures, collecting clinical, lab, and outcome data to identify predictors of severe outcomes, cardiovascular events, and mortality

Builds on Fentalog 1 with more robust enrollment and integration of biomarkers (cfDNA, ECG phenotyping). Aims to deepen mechanistic understanding of fentanyl analog toxicity

NIH-funded multicenter adaptive trial comparing high-dose versus standard buprenorphine induction. UG3 is the manualization/protocol phase; UH3 is the RCT phase starting soon

Large EHR-based dataset linking COVID-era patient demographics, socioeconomic determinants of health (SDoH), and overdose events to identify disparities

Captures bedside toxicology consult cases from >50 sites. Used to track emerging substances, treatment patterns, and outcomes

A forthcoming R01 using multi-center data to model physiologic interactions (e.g., fentanyl + cocaine/methamphetamine) and their impact on outcomes.

Institution-wide initiative integrating clinical, laboratory, and community data streams for overdose surveillance and rapid research translation

Retrospective review of naloxone dosing, timing, and downstream initiation of buprenorphine across the Mount Sinai system

Uses HCUP NIS/NEDS data to evaluate national trends in ED visits, ICU admission, and mortality for opioid or stimulant overdose

Focused national surveillance initiative within ToxIC Registry to detect and characterize emerging synthetic opioids/stimulants

To evaluate the impact of fellowship on career success – still defining outcome metrics to quantify this…

Evaluate the implementation and impact of admin-related curriculum in EM residency conference.

Quantify the impact of sepsis simulations in improving sepsis care. This will be a department supported initiative

A review of the Mount Sinai EMS system's metrics of the ET3 pilot to include what percent qualified to participate, what percent agreed to participate, and tracking the outcomes of those who participated.

An anonymous survey to NYS EMTs and Paramedics evaluating the challenges and barriers to successful implementation of the former CMS ET3 pilot.

Case report on patients who presented to the ED as a result of the January 4th train derailment. To review care needs, rates of imaging, consults, admissions, etc. to describe needs following a blunt trauma MCI.

Evaluate the role for nerve blocks in hip fractures and rib fractures that require transfer to another facility. Were less opioid/pain medications needed? Were pain scores lower?

A review of the Mount Sinai EMS system's metrics of the ET3 pilot to include what percent qualified to participate, what percent agreed to participate, and tracking the outcomes of those who participated.

An anonymous survey to NYS EMTs and Paramedics evaluating the challenges and barriers to successful implementation of the former CMS ET3 pilot.

Proposal to implement air sampling for surveillence of viral pathogens with metagenomic analysis.

Effectiveness of an in situ, interdisciplinary postpartum hemorrhage simulation to improve team readiness, communication, and adherence to hemorrhage management protocols

An investigation assessing how implementation of a revised ED sexual health orderset influences HIV cotesting rates among patients tested for gonorrhea and chlamydia.

A time-motion observational study quantifying the real-world workflow and time burden of STI-related callback tasks performed by ED physician assistants to identify bottlenecks and inform implementation strategies for PrEP initiation during callbacks.

A systematic review synthesizing evidence on behavioral interventions designed to improve initiation, uptake, or adherence to HIV pre-exposure prophylaxis across diverse populations.

Programmatic, research, or education opportunities available in conjunction with AFEM

Write manscript for an analysis already completed. Machine learning for predictors of AUD in Rwandan patients at a trauma center.

Proteomics and other -omics to determine biological pathways affected due to environmental factors in SCD; community engaged reseach monitoring air quality in SCD patients

NLP and community-engaged focus groups to understand social needs related to heat illness in ED patients. Some chart review and some interview/focus groups/qualitative research

Reviewing Trauma team data to analyze and describe the epidemiology and outcomes associated with intentional TBI (assault, suicide) compared to unintentional TBI (MVC etc)

Funded by Abbott pharmaceuticals, this study will evaluate how brain biomarkers for TBI affect physician decisionmaking and the concordance between capillary biomarkers and whole blood biomarkers

Evaluating recent articles from high impact journals to determine the reporting of sociodemographic variables/sdoh in cardiovascular clinical trial articles

NLP and community-engaged focus groups to understand social needs related to heat illness in ED patients. Some chart review and some interview/focus groups/qualitative research

Secondary analysis of differences in naloxone administration, clinical outcomes and resource utlization in patients with protonitazene vs fentanyl overdose in a national multicenter cohort of ED patients

Review article examining current literature on barriers/facilitators to buprenorphine/OUD treatment retention and adherence following initation of BUP in the ED

Retrospective comparison of screening volume and positivity rates for Hep C and HIV screening between nursing, health educator and clinician offer

Various projects involving: Hep C/HIV screening rates/acceptance, positivity and referral rates, appointment attendance, harm reduction provision, naloxone kit dispensing, MOUD administration and prescription

RCT examining fomepizole for acetaminophen overdose

Open-label trial evaluating Rimegepant ODT 75 mg or Zavegepant Nasal Spray 10 mg for ED management of migraine

Phase 2/Phase 3 RCT evaluating CSL889 for sickle cell disease

Qualitative analysis of interviews with ED youth with substance use to gain perspectives on ED based interventions

Adapting an intervention for ED youth with substance use to support linkage to care

Improving ED-based substance use screening and naloxone distribution in the PED (and potentially hospital wide for Kravis Children's)

This project uses interdisciplinary digital care pathways designed to proactively address common barriers to care within Epic MyNextSteps to support patients after they leave the hospital.

Creation of an ED Geriatrics Service that uses an EHR-embedded frailty index to identify at-risk older adults and enroll patients into new interdisciplinary care pathways

Integration of digital tools like Epic ED Bedside into ED Obs Service care pathways in order to screen for health-related social needs and address identified needs before discharge

We are revamping the PEM curriculum offered to the residents during conference. The curriculum will run over 18 months with the intention that it is offered twice in 3 years. Assessment will be done through MCQs, self efficacy questions and structured interviews (mixed methods)

Evaluate the implementation and impact of admin-related curriculum in EM residency conference.

National, multicenter prospective cohort of ED patients with confirmed fentanyl analog exposures, collecting clinical, lab, and outcome data to identify predictors of severe outcomes, cardiovascular events, and mortality

Builds on Fentalog 1 with more robust enrollment and integration of biomarkers (cfDNA, ECG phenotyping). Aims to deepen mechanistic understanding of fentanyl analog toxicity

Mixed-methods evaluation of reasons for end-of-life admissions when not consistent with goals of care

Evaluation of 3-part intervention for management of uncontrolled HTN in the ED

Analysis of ED OCP initiation rates following a single provider education session

Survey study of provider and patient attitudes toward other types of contraception (specifically, long-acting reversible contraception) in the ED as part of a larger project to offer Nexplanon placement in the ED

Identifying gaps in trauma care in NYC including identification, actions, notifications, transport decisions.

Early stages – still identifying project question and goals

chart review of ED visits for HTN to figure out what workup they get and what the disposition is

Systematic Review of 0/1 vs 0/2 hour hsTrop algorithms

Large database analysis – predictive modeling of outcomes in traumatic brain injury

A Novel Global Health Curriculum incorportated into Resident Conference Teaching

We are revamping the PEM curriculum offered to the residents during conference. The curriculum will run over 18 months with the intention that it is offered twice in 3 years. Assessment will be done through MCQs, self efficacy questions and structured interviews (mixed methods)

Evaluate the implementation and impact of admin-related curriculum in EM residency conference.

Evaluate the role for nerve blocks in hip fractures and rib fractures that require transfer to another facility. Were less opioid/pain medications needed? Were pain scores lower?

NIH-funded research study that will test three interventions — redesigning the ED experience, nurse-led telephone-based care, and transitional care delivered by paramedics. Each intervention is designed to reduce future ED visits and hospital admissions and improve quality care and care coordination for patients with dementia who are discharged home from the ED. (Coordination with NYU / Sloan / UW)

Training to help FDNY EMS and Fire Operations work more collaboratively

A needs assessment was done to help formulate our specific rural / low resource curriculum. Currently giving lectures and planning for pre-post surveys as well as an end of year re-assessment of comfort with rural specific topics. Pertinent as the ACGME is putting more emphasis onto low – resource medicine.

Assess the impact of training 250 nurses in basic emergency care skills on mortality pre vs post-intervention at Bugando Medical Center in Tanzania.

We are revamping the PEM curriculum offered to the residents during conference. The curriculum will run over 18 months with the intention that it is offered twice in 3 years. Assessment will be done through MCQs, self efficacy questions and structured interviews (mixed methods)