I Scream, You Scream, We All Scream for Lactate.

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    I Scream, You Scream, We All Scream for Lactate.

    We love our lactates and want to protect them from every slip and fall.  But are they a bit more resilient than we think?

    Jones et al. concluded that point-of-care venous lactate in healthy patients does not significantly change over a course of 15 minutes either at -1˚ C or 23˚ C (room temperature) as well as with or without a tourniquet.

    –       Prospective randomized trial of 63 healthy patients divided into 3 groups

    –       Group 1: venous lactate drawn without tourniquet and placed on ice (-1˚ C)

    • Over 15 minutes, lactate increased 10%

    –       Group 2: venous lactate drawn without tourniquet and left in room air (23˚ C)

    • Over 15 minutes, lactate increased 25%

    –       Group 3: venous lactate drawn with a tourniquet placed 5 minutes before

    venipuncture and placed on ice

    • Over 15 minutes, lactate increased 6%

    –       No significant differences in mean lactate concentrations were found among any group (p>0.90)

     

    Jones AE, Leonard MM, Hernandez-Nino J, Kline JA. Determination of the effect of in vitro time, temperature, and tourniquet use on whole blood venous point-of-care lactate concentrations. Acad Emerg Med. 2007 Jul;14(7):587-91. Epub 2007 May 18

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