The number of lung transplant recipients is increasing. With improved immunosuppressant medications, pts are living longer. The 5-yr survival rate is now approximately 60%.
When evaluating a lung transplant pt who is < 1 yr following transplant, who is presenting with cough, SOB, malaise, and/or hypoxia, what could be possible explanations?
1) Acute rejection: Occurs in up to 40% of patients and is treated with corticosteroids
- Bacterial infections usually occur in the early stages following transplant, with Pseudomonas being the predominant organism
2. CMV is the most common organism affecting up to 33% of pts during the first year after transplant