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Lidocaine Pretreatment in Asthmatics

In asthmatics requiring endotracheal intubation airway stimulation can induce severe reflex-mediated bronchoconstriction. This reflex is neurally mediated in part by the vagal nerves. Is there any evidence for the use of lidocaine pretreatment to prevent reflex bronchoconstriction?   TL;DR: Based on the studies below, pretreatment with lidocaine prior to intubating asthmatics is not recommended.  The evidenceRead more

Bandemia with Normal WBC Count

Is bandemia with a normal WBC count concerning?   TL;DR: Bandemia is concerning even in the absence of leukocytosis and/or abnormal temperature   Drees et al evaluated whether patients admitted to the hospital with a normal WBC and elevated bands were at higher risk for infection or in-hospital death -Retrospective cohort study including all admittedRead more

Google Deep Learning for EHR

Google recently published a study online (not peer reviewed) of its AI system that predicts medical outcomes such as in patient mortality, readmission, etc There is a lot of technical jargon in the paper, but here is a brief summary: -Previously, predictive models required selection of variables and standardization of data, which is generally veryRead more